Speaker: Helen Moore
Title: Systems Modeling in Biopharma
Abstract: Quantitative systems pharmacology (QSP) models are increasingly being used for decision making in the biotechnology/pharmaceutical (biopharma) industry. QSP models are typically systems of ordinary differential equations with some mechanistic level of detail of the disease and a therapy. Parameters in a QSP model may be estimated from data, or obtained from the literature or from input from disease/biology experts. Once parameter values or distributions are determined, a QSP model can be used for predictive purposes. I will show some examples of QSP models used in projects for various applications in the biopharma industry. I will also mention some of the issues and open problems for the use of QSP models.