The Adolescent Brain Cognitive Development (ABCD) study is a national Consortium study funded by the National Institutes of Health. To date, 11,875 children (including both singletons and twins) ages 9-10 have been enrolled across 21 data collection sites with the goal of investigating brain and behavioral development between late childhood and young adulthood. Because participants will complete comprehensive behavioral and neuroimaging assessments longitudinally, the ABCD Study is well-positioned to answer questions about the developing brain and the many childhood experiences that shape social, emotional, intellectual, and physical growth as well as mental health. Drs. Luciana and Iacono direct the University of Minnesota’s ABCD data collection site. They will provide an overview of the study and will discuss its potential to inform our understanding of adolescent mental health.